Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is associated with adverse effects especially on the bones and kidney. While nowadays it is mostly diagnosed at an asymptomatic stage, patients with overt involvement of the target organs at the time of diagnosis are still encountered.Aim: To explore the frequency of disease complications already present at the time of diagnosis in a cohort of patients with sporadic PHPT who meet the current surgical guide...

Background: Sheehan’s syndrome occurs after a delivery complicated with hemorrhage causing ischemic pituitary necrosis and panhypopituitarism. It is rare for a patient with Sheehan’s syndrome to obtain recovery of the pituitary function. We report the case of a patient with Sheehan’s syndrome who obtained a spontaneous pregnancy 2 years after the initial diagnosis.Case presentation: A 23-year-old-woman, without a significant personal medic...

Background: Craniopharyngioma is a rare epithelial tumor of the central nervous system, affecting both children and adults and associated with significant morbidity.Objective: To study the postsurgical evolution of craniopharyngioma in adults after total or incomplete surgical resection.Material and methods: We performed a retrospective review of craniopharyngioma patients evaluated in the National Institute of Endocrinology in Buc...

Aim: Has testosterone undecanoat 1000 mg intramuscular injection (NebidoR; Bayer), 1 at 3month, negative effect on prostate? For this purpose, we appreciate the prostatic volume (see Pisoschi, this congress) and PSA (this study) in hypogonadic patients after testosterone injection up to 11 years.Material and method: A. PSA (ng/ml) was done in Bucharest accredited laboratories.B. Patients: PSA analysis was done before tre...

Aim: Re-Analysing (study starting in 2007) the effect of injectable testosterone undecanoat depot (TUD) in hypogonadic patients.Material-method: A. Patients: at onset 278 men with hypogonadism (median: 61 y).B. Distribution: by decade (starting with 20y); no =6, 17, 25, 70, 86, 55, 18, 1.C. TUD (NebidoR-Bayer) 1000 mg injected one/3 months i.m.D. Prostate volume (PV) apprecia...

Background: Empty sella (ES) is often an incidental imaging finding, associated or not with the following symptoms: headache, hypopituitarism or visual impairment. Two etiological forms are described: primary ES due to a combination of increased spinal fluid pressure and a defect in the sella diaphragm and secondary ES due to the shrinkage of the pituitary gland (after pituitary surgery, radiation, apoplexy, hypophysitis or neurosarcoidosis).Clinical cas...

Aims: To evaluate the prevalence of antinuclear antibodies (ANA) in patients with chronic autoimmune thyroiditis (CAT) associated with periodontal disease (P.D).Material and methods: 42 patients with TCA and BP were tested for ANA (Group 1) and 50 patients with TCA without BP (Group 2). Inclusion criterias – absence of other autoimmune diseases associated with positive ANA patients. Thyroid hormone deficiency has established thyroid function. Patien...

Introduction: Riedl thyroiditis is a rare thyroid disorder of unknown etiology (autoimmune assumed), in which the gland is invaded by dense fibrous tissue, that extends in the vicinity. Goiter is usually painless and can be accompanied by other fibrous affections (retroperitoneal fibrosis, sclerosing cholangitis, mediastinal fibrosis).Case presentation: Patient, 39 years old, smoker, from nonendemic area, initially presents in 2011 with voluminous polyno...

Aggressive pituitary tumors (APT) causing Cushing’s Disease are very rare, difficult to treat. The majority of Crooke’s corticotropinomas are macroadenomas, exhibiting rapid growth, resistance to conventional treatments, a high recurrence rate. To date, there is no fully effective method of treatment for these tumors. Pituitary carcinomas (PC) are defined by distant metastasis. PC is exceedingly rare, comprising only 0.1–0.2% of all pituitary neoplasms but APT m...

Background: Primary hyperparathyroidism is usually a long evolving disease before the diagnosis, thus patients who are not diagnosed by routine screening tests may have a lot of complications affecting the bone, kidney, bone marrow.Aim: Pointing out the possibility of fast recovery not only for bone mass.Material: We present a case of primary hyperparathyroidism, a female patient 66 years old, sent to emergency room, dehydrated, as...